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miscellaneous
gowning room
Low Endotoxin
ISO Class 5
GRADE A
Product Contact Surfaces
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Iso Class 5
Grade b
ISO Class 7/8
GRADE C/D
V.A.L.
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Clean surfaces in a Grade A environment are crucial. These environments are where critical medications are made that save lives. Therefore, every inch of each surface needs to be accounted for when choosing products to clean and disinfect. Products that are easy to transfer and use are necessary for Grade A environments.
cleaning Biosafety Cabinets
cleaning Restricted Access Barrier SYSTEM
cleaning Isolators
cleaning Unidirectional Air Flow Hoods
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PROSAT® Sterile™ Polynit Heatseal Wipes
Sterile CyQuanol™ Disinfectant
EasyReach™ Cleaning Tool and Pad
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Daily decontamination is necessary to eliminate contaminants in a biosafety cabinet. The use of proper tools greatly help clean effectively and maintain a sterile environment.
Cleaning a Biosafety Cabinet
Grade A: Biosafety Cabinets
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It's imperative to keep isolators cleaned and disinfected to protect the product and the operator. Each surface must be cleaned or disinfected with a new wipe or pad to ensure surface sterility.
Cleaning an Isolator
Grade A: Isolators
Unidirectional Air flow hoods must be kept clean to ensure product safety and sterility. It's imperative to clean each surface with overlapping strokes to ensure proper coverage.
Cleaning a UDAF Hood
Grade A: Unidirectional Air Flow Hoods
There are various types of RABS, making it important to assess the types of cleaning tools that are needed to get proper access and ensure proper coverage in order to maintain a sterile environment.
Cleaning a RABS
Grade A: Restricted Access Barrier System
Grade A
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Grade B
Grade B areas have strict procedures and protocols to maintain their level of sterility. These larger areas have strict microbial and particle limits that need to be met. Products introduced into the area need to be sterile or autoclavable so they do not introduce viable contamination into the environment. Proper techniques need to be utilized to properly clean and disinfect ceilings, walls, floors, tables and equipment.
Cleaning Windows
Cleaning the Ceiling
Cleaning the wall
Cleaning the floor
Cleaning the table and equipment
Cleaning Pass-Through
Grade B: Windows
Windows can be a challenging surface to clean because they need to be disinfected as well as cleaned. It's important to follow any disinfectant with a rinse to ensure that there is no residue left on the surface, leaving streaks behind.
VertiKlean® MAX™ Sealed Edge Mop
PROSAT® Polynit Heatseal Wipes
Compact Bucket System
VertiKlean® MAX™ Sterile Sealed Edge Mop
When it's time to clean a Grade B room, the ceiling is cleaned first since it's the cleanest point in the room. It's important to use overlapping strokes, starting in the corner of the room farthest from the exit door while moving to the other side of the room.
Grade B: Ceilings
The walls are to be cleaned after the ceiling. There are several methods that can be used, such as: vertical overlapping strokes, horizontal overlapping strokes, or a hybrid of the two.
Cleaning the Wall
Grade B: Walls
The floor is the last surface to be cleaned inside of the room. Start in the corner furthest from the exit door. Using the S-curve or Place and Pull method with overlapping strokes, work your way to the exit door, so as not to step on a clean area.
Cleaning the Floor
Grade B: Floors
Anticon® Sterile MicroQuilt™ Wipe
Tables have various uses. It's important to keep these areas cleaned and disinfected to prevent cross-contamination. All the equipment and items on the table are cleaned first before the table surface.
Cleaning the Table and Equipment
Grade B: Table and Equipment
PROSAT® Sterile™ Delta Wipes
Cleaning a pass-through is similar to a room, where the ceiling is first, then the walls and doors and lastly the floors. When wiping, it's important to use overlapping strokes.
Grade B: Pass-Throughs
Grade C/D
Grade C/D environments are less critical but no less important when cleaning and disinfecting surfaces. Although this is not a sterile area, ceilings, walls, floors, tables and equipment must be cleaned and disinfected regularly per a company’s SOPs. Tools are available to make these jobs easier and more efficient.
Cleaning the equipment
Cleaning Irregular Surfaces
CyQuanol™ Disinfectant
When it's time to clean a Grade C/D room, the ceiling is cleaned first since it's the cleanest point in the room. It's important to use overlapping strokes, starting in the corner of the room farthest from the exit door while moving to the other side of the room.
Grade C/D: Ceilings
Grade C/D: Walls
Grade C/D: Floors
MicroQuilt Wipes
PROSAT® Meltblown Polypropylene Wipes
Equipment has various uses. It’s important to keep these areas cleaned and disinfected to prevent cross-contamination paying close attention to irregular surfaces.
Cleaning the Equipment
Grade C/D: Equipment
Endotoxins are a big concern for pharmaceutical and medical device manufacturing. Once endotoxins are present, it's difficult to remove them. It is therefore important to control the level of endotoxins in all materials used in the production of drug products and medical devices, including products used to clean the environments.
Sterile Polynit Heatseal LE Wipes
HydroKlean
PROSAT® Sterile™ Polynit Heatseal LE Wipes
Contec has a family of low endotoxin certified products including presaturated wipes with WFI, dry knitted wipes, dry nonwoven wipes, a hydrogen peroxide cleaner, and 70% IPA/ WFI.
Certified low endotoxin products
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Gowning Room
The Gowning room is the first step to entering a cleanroom environment. It’s imperative that it is cleaned and disinfected on a regular basis according to a facility’s SOP’s. Gowning rooms can be small or large depending on the facility. It’s important to pick tools that work best in the space and do not cause unnecessary strain for the user..
Cleaning Benches and Supply Racks
Double Polypropylene Bucket System
Gowning Room: Ceilings
Gowning Room: Walls
Non-Sterile CyQuanol™ Disinfectant
The floor is the last surface to be cleaned inside of the room. Start in the corner furthest from the exit door. Using the S-curve or Place and Pull method with overlapping strokes, work your way to the exit door so a not to step on a clean area.
Gowning Room: Floors
ReFIBE Wipes
Benches in a gowning area can be made of several different materials. It's important to choose the cleaning products that are safe to use on those materials to prevent corrosion and pitting.
Gowning Room: Benches and Supply Racks
SATWIPES®
It's important to clean all irregular surfaces before cleaning and disinfecting the room. These surfaces can be vents, lights door knobs, light switches and supply racks.
Gowning Room: Irregular Surfaces
Miscellaneous
There are often areas in a Cleanroom that are overlooked and need special cleaning protocols as they are different or difficult to clean. These areas still need to be cleaned regularly according to the facility’s SOPs. Select the area for details for products to use and how to clean them efficiently.
Cleaning Softwall Curtains
Cleaning Sinks
Unclassified Hallways
Contec IPA
DualClean Softwall Strip Cleaner
Softwall curtains are difficult to clean due to their flexibility. It's imperative to clean both sides of the curtain, starting at the top of the strip down to the bottom of the strip.
Miscellaneous: Softwall Curtains
NeutraKlean
MicroGenesis Mop
All areas of a cleanroom need to be cleaned and disinfected even if they are not considered a sterile area, such as: hallways, ceilings, walls, floors and other surfaces. These surfaces must be disinfected on a regular basis.
Cleaning Unclassified Hallways
Miscellaneous: Unclassified Hallways
