4 FAQs About ARNIs

1. How much do ARNIs cost?

3. Can I take an ARNI if I have kidney disease?

4. Do ARNIs fix all the symptoms of heart failure?

2. Are ARNIs safe?

9. Will I have to take these medications forever?

8. Will I be able to afford this medication?

7. JAK inhibitors are still pretty new – are you sure they’re safe?

6. I read that JAK inhibitors increase the risk of blood clots. Should I be worried?

5. Can taking a JAK inhibitor cause cancer?

4. Why do I need to get certain vaccinations first?

3. Will taking a JAK inhibitor shut down my immune system?

2. If one JAK inhibitor doesn’t help me, does that mean none of them will?

1. Which JAK inhibitor is most likely to help me?

Essential Facts About ARNIs

Most Medicare and insurance policies cover ARNIs, but some providers have more restrictive policies and may not cover the entire cost of the medication or require prior authorization before covering it, says Dr. Pirlamarla. Some insurers may also require you to try an ACE inhibitor or an ARB before they’ll approve an ARNI.

1. How much do ARNIs cost?

Essential Facts About ARNIs

Although all medications have side effects, studies have shown that ARNIs are safe to take, says Pirlamala. What’s more, “ARNIs have had a profound positive impact on patient survival, on related conditions, and on longevity,” she says.

2. Are ARNIs safe?

Essential Facts About ARNIs

3. Can I take an ARNI even though I have kidney disease?

Essential Facts About ARNIs

Some people with kidney disease can take ARNIs, but others won’t be able to. (It’s thought that very low blood pressure can harm the kidneys in people with kidney disease.) If your doctor recommends starting an ARNI, your kidney function will be carefully monitored while you’re taking the medication. “A certain amount of change in kidney function is to be expected,” says Pirlamarla. “But we’ve found that ARNIs are actually protective of kidney function in the long term.” Even people with advanced kidney disease may be able to use ARNIs, but with extreme caution, she says. “It’s important to have a conversation with a kidney specialist about what, and how much, to use.”

“A certain amount of change in kidney function is to be expected,” says Pirlamarla. “But we’ve found that ARNIs are actually protective of kidney function in the long term.” Even people with advanced kidney disease may be able to use ARNIs, but with extreme caution, she says. “It’s important to have a conversation with a kidney specialist about what, and how much, to use.”

Heart failure drugs aren’t intended to be standalone treatments for heart failure. Lifestyle habits, such as eating a heart-healthy diet, being physically active, staying at a healthy weight, quitting smoking, and avoiding or limiting alcohol and caffeine are all important parts of controlling your condition.

4. Do ARNIs fix all the symptoms of heart failure?

Essential Facts About ARNIs