That’s the key to understanding ankylosing spondylitis — an inflammatory form of arthritis affecting the spine. And the goal of treatment is to stop that inflammation.
What is inflammation?
It’s your immune system’s way of fighting off viruses, bacteria, and germs.
is an autoimmune disease in which your immune system mistakenly attacks the spine. Immune system proteins like tumor necrosis factor-alpha and interleukin
17-A overpopulate and signal the inflammatory process that causes pain, stiffness, and swelling along the spine.
Let's start with
But RA researchers didn’t stop there.
as well as cause new bone to form,
which fuses the spine and can result in a stooped posture.
deliver an even more targeted approach.
Over time, this can
Treatment often starts with
to relieve symptoms. But sometimes these medications aren’t enough.
are a type of disease-modifying antirheumatic drug (DMARD) that targets specific inflammatory proteins, including
TNF-alpha and IL-17.
By blocking the signaling pathways
of these proteins, biologics can prevent the inflammation that causes your symptoms, and may help slow disease progression and reduce your risk of joint damage.