Consumers Guide GLP-1s for Obesity Animation How GLP-1 agonists and dual GIP/GLP-1 agonists work

are medications that can help you lose weight by increasing feelings of fullness, regulating blood sugar, and slowing down digestion.

GLP-1 agonists and dual GIP/ GLP-1 agonists

GLP-1 and dual GIP/GLP-1 agonists mimic natural hormones in the body that are produced in the lining of the intestines.

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When you eat, GLP-1 and GIP hormones trigger the pancreas to release insulin, which helps prevent spikes in blood sugar after meals. Keeping blood sugar stable can help curb cravings and overeating.

INSULIN

GLP-1 also blocks the pancreas from secreting glucagon, a hormone that raises blood sugar. GIP triggers a small increase in glucagon, which may sound counterintuitive, but it helps your body manage energy and derive nutrients from food.

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During digestion, GLP-1 slows the rate at which food empties from your stomach into the intestines, reducing how fast glucose (sugar) is absorbed into the bloodstream.

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Finally, both GLP-1 and GIP act on receptors in your brain to help reduce appetite and food cravings. This can decrease the amount of food you eat and result in weight loss.

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Dual GIP/GLP-1 agonists are especially effective for helping people with obesity lose weight.

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