Work with your doctor to identify the parts of your body most affected by psoriatic arthritis (known as PsA domains). “Understanding the extent of the disease does
make a difference,” says Dr. Sohn, “because some IV biologics work better for
certain domains.”
These may include:
Identify Your PsA Domains
Biologics affect how your immune system fights infection, so it’s important to stay up to date on routine vaccinations. Sohn also recommends practicing good hygiene, avoiding crowded spaces, and wearing a mask, when appropriate.
Strengthen Your Immune System
Your doctor will test you for latent infections such as tuberculosis, hepatitis B, and hepatitis C. Because biologics calm your immune system, they can sometimes allow a quiet, inactive infection to “wake up” and make you sick. Testing for these first ensures it’s safe to start treatment with biologics.
Complete an Infection Screening
Premedications, such as antihistamines, and the treatment itself can cause drowsiness, so be sure to plan a ride home.
“In the beginning everyone should plan to take it easy that day and have transportation arranged,” says Sohn.
Arrange Transportation
Imaging of the hands, feet, or spine can help create a baseline understanding of any existing joint damage. This allows doctors to track how well the biologic is working
over time.
Your doctor may also check inflammation markers, such as C-reactive protein and erythrocyte sedimentation rate, to measure disease activity, says Sohn.
Drink plenty of water in the days leading up to the infusion. Staying hydrated can make veins easier to access and may help reduce postinfusion headaches. It’s also a good idea to bring a water bottle with you on infusion day.
Stay Hydrated
Assess Joint Damage
Tests
Dress in loose, comfortable clothing and bring a few items to help relax and pass the time. Pack a favorite blanket and a fully charged tablet loaded with movies, shows, or podcasts. Don’t forget your headphones, in case you’re in a shared space.
Prep a Comfort Kit
• Joints (peripheral arthritis)
• Spine (axial disease)
• Fingers or toes (dactylitis)
• Tendon or ligament attachment points (enthesitis)
• Nails
• Skin