Migraine-specific acute medications are used to treat a migraine attack as soon as it starts. They tend to work best when taken as early as possible after the start of symptoms.
Migraine-specific medications for acute attacks:
• Triptans
• Gepants
• Ergotamines
• Ditans
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Migraine-Specific Acute
Medications
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Non-specific medications are widely used to treat mild to moderate pain and ease nausea symptoms in people with migraine. You can find many of these over-the-counter, but others will need a healthcare provider’s prescription.
Non-specific medications:
• Acetaminophen
• Non-steroidal anti-inflammatories
• Anti-nausea medications
• Opioids (not recommended for migraine)
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Non-Specific Medications

Several FDA-approved neuromodulation devices are designed to treat acute migraine attacks. These devices can be worn on the head, neck or arm.
Devices used to treat acute attacks:
• Cefaly (External Trigeminal Nerve
Stimulator)
• Nerivio (Remote Electrical
Neuromodulation)
• gammaCore (Vagus Nerve Stimulator)
• sTMS mini (Transcranial Magnetic Stimulator)
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Neuromodulation devices

Behavioral Therapies can help manage pain and anxiety. They are useful as a daily practice and in the early stages of a migraine attack. These therapies can be safely combined with migraine-specific and non-specific medications.
Behavioral approaches for migraine relief:
• Mindfulness
• Biofeedback
• Relaxation techniques and deep breathing
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Behavioral therapies

Many people with migraine use supplements and natural therapies to treat the symptoms of migraine like pain, nausea, and muscle soreness. It is important to tell your healthcare provider about all of the treatments you are using.
Supplements and natural remedies for acute treatment:
• Peppermint oil and spearmint oil
• Caffeine - with limitations
• Ginger - for nausea
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Supplements
and natural therapies
