Psoriasis
is much more than a skin disease. That’s why, when topical medications aren’t enough to treat it, you may need a biologic drug, which helps stop the inflammatory process that causes psoriasis.
If you have psoriasis, your immune system — which usually attacks invaders like bacteria
and viruses —
JAK inhibitors
starts attacking your skin with inflammation, from the inside out.
Most likely, the immune system produces too many cytokines, specifically interleukin 23 and 12.
These proteins signal cellular and inflammatory responses that ultimately cause psoriasis plaques.
1980s
Skin cells take about a month to mature, move to the skin surface, and shed.
Healthy skin
Let's start with
This process is sped up, and premature skin cells build up.
psoriasis
To treat plaques, topical medications like corticosteroids are applied to affected skin.
Biologics start working before plaques form.
Biologics
Biologics are immunosuppressants but they’re much more targeted than traditional systemic medications.
These drugs block specific proteins and cells, which disrupts the cascade of events that leads to psoriasis plaques — and people with psoriasis end up with less inflammation throughout the body and clearer skin
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