Factors Impacting Adherence
Practical Approaches for Improving Adherence
Inadequate medical and social support
Financial/insurance issues
Polypharmacy
Poor patient-provider communication
Treatment-related adverse events
Comorbidities
Cognitive issues
Advanced patient age
Development of tailored recommendations such as coaching and adherence aids (smartphone reminders/text messages, smart bottle pill reminders, WiseBag, etc)
Proactive, regular assessment of adherence, possibly involving pharmacokinetic drug monitoring
Involvement of oncology pharmacists and nurses in patient education, assessment, and management
Proactive identification and management of treatment-related adverse events
Adherence risk assessment to identify patients at increased risk of nonadherence and any potential barriers
Education of patients and family members about therapy and importance of long-term adherence
Clear and regular communication with patient
