What women need to know about hormone replacement therapy
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Jessica Shepherd, M.D., board-certified OB/GYN, breaks down perimenopause, menopause, and hormone replacement therapy (HRT). From symptoms and lab testing to lifestyle hacks and muscle-building tips, she shares expert guidance to help you take charge of your health.
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This is a phase that (literally) every woman goes through and consumes an average of 4 years to up to a decade (!!) of your life. Yet, it can feel isolating—like you have to relearn the blueprint to your body. And you do. While it may seem overwhelming, it's completely possible with the right support. That’s where we come in.
With that, we officially welcome you to perimenopause with what we hope will be a go-to resource for navigating this transition with confidence, clarity, and community.
editor
Molly Knudsen, M.S., RDN Hannah Margaret Allen
credits
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BACK TO TOP
Society has convinced women to neglect their strength. We’ve been encouraged to opt for thinness over… well, over everything—physical health, mental health, our sense of self.
Finally, after a lifetime of being told to eat less and stick to cardio, and ultimately shrink ourselves, we’re seeing women fill up their plates, pick up the heavy weights, and step into their power.
At mindbodygreen, we believe that cultivating this strength lays the foundation for a long, healthy, and joyous life. Strength is physical, mental, and emotional. Strength is resilience and self-discovery. Strength is feminine, it’s beautiful, and it’s bold. And we acknowledge that a strong woman comes in many forms.
of sports research is dedicated to women
of the autoimmune conditions impact women
of girls stop playing sports by age 14 due to low body confidence
LEARN
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At mindbodygreen, we cut through the confusion with expert-backed guidance on hormone changes, symptom management, and lifestyle strategies so that you understand what’s happening and take an active role in your well-being.
I can’t think clearly.
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Navigating lifestyle modifications & HRT
your peri/menopause+ guide
WELCOME TO PERIMENOPAUSE.
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Bioidentical vs. Synthetic HRT: What Experts Want Every Woman To Know -->
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SYMPTOM MANAGEMENT
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Whether you’re curious about managing symptoms, hormone therapy, or building strength, here are the top insights from the mindbodygreen podcast
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The surprising brain symptoms of perimenopause
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The best brain health tips for women
Lisa Mosconi, PHD
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The most common health myths, debunked
Marty Makary, M.D.
How to eat for longevity, calm cravings, & balance blood sugar
Amy Shah
What to know about muscle, metabolism & mindset
Jaime Seeman
Building and maintaining muscle during menopause is essential for bone health, metabolism, and longevity. In these podcasts, experts share the science and strategies to help you train smarter and feel stronger at every age.
Building strength & resilience
Why so many women are burnt out & what to do about it
Angela Foster
Why women live longer, but not better
Maddy Dychtwald
How to build lean muscle & eat the right amount of protein
Gabrielle Lyon, M.D.
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Michelle Shapiro, R.D.
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Ashley Damaj, BCBA, CPT
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peri/menopause+ Support shop
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Sexual health is part of your well-being
Jila Senemar, M.D., FACOG
Why do I have joint pain?
WELCOME TO PERIMENOPAUSE.
I can’t think clearly.
Why is waking up at 3 am my new normal?
The stakes are real: Perimenopause lasts 4 to 10 years on average, and postmenopause accounts for over a third of your lifespan.
In my 16 years at mindbodygreen, I've watched wellness trends come and go. But what's happening right now? This feels different. We're finally seeing lifestyle modification and hormone therapy work together to not just manage symptoms, but actually extend healthspan.
Why do I have joint pain?
I can’t think clearly.
Why is waking up at 3 am my new normal?
WELCOME TO PERIMENOPAUSE.
Weight appears overnight, especially around your waist. Energy plummets. Sleep vanishes.
Why do I have joint pain?
You've been doing everything "right"—but your body isn't cooperating. And you're wondering: Is this just my life now?
Here's the truth: Nearly 2 million US women enter perimenopause each year, yet 49% feel they should simply push through the struggle. That means roughly 1 million women annually are suffering in silence—when they don't have to.
That's why we created your peri/menopause+ guide. You'll learn the right questions to ask your practitioner and discover evidence-based strategies tailored to your specific needs.
Because waiting isn't a strategy, and your health can't wait.
—Colleen Wachob, mindbodygreen co-founder and co-CEO
dive deeper with our peri/menopause+ course
Approach perimenopause with clarity—not confusion. This doctor-led, science-backed course provides 15 hours of on-demand lessons and tools for navigating HRT, nutrition, supplements, sleep, and mood.
ENROLL TODAY -->
experts cited
Emily Marquis, Board-Certified Health Coach
Lynn Mason, N.P.
Ana Maria Kausel, M.D.
Amy Killen, M.D.
Jila Senemar, M.D., FACOG
Michelle Shapiro, R.D.
Mariza Snyder, D.C.
Wendie Trubow, M.D., MBA
Wendy Troxel, Ph.D.
Vonda Wright, M.D.
Ashley Damaj, BCBA, CPT
Maddy Dychtwald
Angela Foster
Mary Claire Haver, M.D.
Gabrielle Lyon, D.O.
Marty Makary, M.D.
Lisa Mosconi, Ph.D.
Sara Reardon, P.T., DPT
Jessica Shepherd, M.D.
sources
Journal of Women’s Health (Larchmt)
The Journal of Steroid Biochemistry and Molecular Biology
NNABI The Peri Power Report
disclaimer: The information provided on this page is for educational purposes only and is not intended as medical advice. It should not be used as a substitute for professional diagnosis or treatment. Always consult with your healthcare practitioner for personalized guidance and care plans.
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87%
of women going through menopause have hot flashes daily
2/3
of women report sleep disturbances in perimenopause
20-32%
lower risk of Alzheimer’s in women who started HRT within 5 years
after menopause
20
bills in 12 states are pushing for better menopause care
80%
of OB/GYN residents feel "barely comfortable”with menopause
SHOP
20-32%
2/3
lower risk of Alzheimer’s in women who started HRT within 5 years
after menopause
of girls stop playing sports by age 14 due to low body confidence
Bioidentical vs. Synthetic HRT: What Experts Want Every Woman To Know -->
Thinking About HRT? These 9 Symptoms Might Be Your Sign -->
This Flawed Study Set Women’s Health Back By Decades (& You Probably Still Believe It) -->
Bioidentical vs. Synthetic HRT: What Experts Want Every Woman To Know -->
Thinking About HRT? These 9 Symptoms Might Be Your Sign -->
hormone therapy
This Flawed Study Set Women’s Health Back By Decades (& You Probably Still Believe It) -->
Bioidentical vs. Synthetic HRT: What Experts Want Every Woman To Know -->
Thinking About HRT? These 9 Symptoms Might Be Your Sign -->
Cream, Patches, Pellets, Pills… What Are The Treatment Options For HRT -->
hormone therapy
food & fitness
I Swapped Cardio For Weightlifting During Perimenopause & Here's What Happened -->
Your guide to HRT & lifestyle changes for menopause
Jila Senemar, MD, FACOG
managing hormones & symptoms
Whether you’re curious about managing symptoms, hormone therapy, or building strength, here are the top insights from the mindbodygreen podcast
Building strength & resilience
3 thing all women 35+ need to hear
What women need to know about hormone replacement therapy
Jessica Shepherd, M.D., board-certified OB/GYN,breaks down perimenopause, menopause, and hormone replacement therapy (HRT). From symptoms and lab testing to lifestyle hacks and muscle-building tips, she shares expert guidance to help you take charge of your health.
LISTEN -->
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Your guide to HRT & lifestyle changes for menopause
Jila Senemar, MD, FACOG
Your guide to HRT & lifestyle changes for menopause
Jila Senemar, MD, FACOG
Your guide to HRT & lifestyle changes for menopause
Jila Senemar, MD, FACOG
Your guide to HRT & lifestyle changes for menopause
Jila Senemar, MD, FACOG
Your guide to HRT & lifestyle changes for menopause
Jila Senemar, MD, FACOG
Your guide to HRT & lifestyle changes for menopause
Jila Senemar, MD, FACOG
Muscle, metabolism, & mindset for women
Jamie Seeman, M.D., OBGYN
Muscle, metabolism, & mindset for women
Jamie Seeman, M.D., OBGYN
How to fuel smarter, train better, & build lean muscle in midlife
Ashley Damaj, BCBA, CPT
How to fuel smarter, train better, & build lean muscle in midlife
Ashley Damaj, BCBA, CPT
How to fuel smarter, train better, & build lean muscle in midlife
Ashley Damaj, BCBA, CPT
How to fuel smarter, train better, & build lean muscle in midlife
Ashley Damaj, BCBA, CPT
How to fuel smarter, train better, & build lean muscle in midlife
Ashley Damaj, BCBA, CPT
Sexual health is part of your well-being
Jila Senemar, M.D., FACOG
The best time to start resistance training
Jamie Seeman, M.D., OBGYN
Your DNA isn’t your destiny
Vonda Wright, M.D.
Sexual health is part of your well-being
Jila Senemar, M.D., FACOG
The best time to start resistance training
Jamie Seeman, M.D., OBGYN
Here's the truth: Nearly 2 million U.S. women enter perimenopause each year, yet 49% feel they should simply push through the struggle. That means roughly 1 million women annually are suffering in silence—when they don't have to.
The stakes are real: Perimenopause lasts 4 to 10 years on average, and postmenopause accounts for over a third of your lifespan.
In my 12 years at mindbodygreen, I've watched wellness trends come and go. But what's happening right now? This feels different. We're finally seeing lifestyle modification and hormone therapy work together to not just manage symptoms, but actually extend healthspan.
That's why we created your peri/menopause+ guide. You'll learn the right questions to ask your practitioner and discover evidence-based strategies tailored to your specific needs.
—Colleen Wachob, mindbodygreen co-founder and co-CEO
Why do I have joint pain?
Why do I have joint pain?
I can’t think clearly.
Why is waking up at 3 am my new normal?
WELCOME TO PERIMENOPAUSE.
Weight appears overnight, especially around your waist. Energy plummets. Sleep vanishes.
You've been doing everything "right"—but your body isn't cooperating. And you're wondering: Is this just my life now?
Because waiting isn't a strategy, and your health can't wait.
Because waiting isn't a strategy, and your health can't wait.