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How It Works
Built-in near-field communication (NFC) reader enables you to pull up your custom protocols and results with a single tap, saving you precious time.
Easy-to-use touchscreen allows you to quickly set up your experiments, use preconfigured analysis methods, and view tutorial videos.
Superior optical system includes a xenon flash lamp and features an ultra-cooled photomultiplier tube (PMT) to -5°C for excellent sensitivity.
Optional SmartInject™ system enables you to expand your lab’s capabilities to include flash applications such as dual luciferase and ATP assays.
QuickSync technology automatically delivers data to workstations, eliminating the need to retrieve data directly from the instrument.
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Cell approaching the nozzle
Cell ejected from the nozzle
Cell detected at the nozzle
Eyewitness proof of monoclonality
A high resolution and large depth-of-field camera is used to capture a time-sequence of 5 images as a single cell is deposited into the well. Users have the option of measuring in brightfield mode or with the f.sight™ model, fluorescent sorting is also available.
The system continues to eject and deflect droplets until a droplet containing a single cell is detected.
The droplet is ejected and immediately deflected into waste.
The system can recognize and sort cells based on size and morphology. Hence, debris/dead cell can be recognized independently.
Debris Event
The system continues to eject and deflect droplets until a droplet containing a single cell is detected.
When no cells are detected in the nozzle, the solution is vacuumed away to waste.
Zero Cell Event
The system continues to eject and dispose of droplets until a droplet containing a single cell is detected.
The droplet with >1 cell is ejected and immediately vacuumed into the waste.
Multi-Cell Event
The system detects >1 cell in the nozzle.
A single cell has been dispensed into the well successfully. The nozzle is positioned over the next well until another single cell is detected.
The cell lands in the dedicated well.
The vacuum stops and a droplet containing a single cell is ejected.
The system detects and images a single cell.
Single Cell Event
The core of the CloneSelect Single-Cell Printing
technology lies in the disposable cartridge and high-resolution
camera. The cell-containing sample is pipetted into the cartridge, where an external piezo-driven actuator is used to eject cell-containing droplets out of the cartridge nozzle. The camera captures a sequence of events to determine the cell number in each droplet.
Nozzle
Cartridge
utilize a patented, microfluidics-based single cell depositing technology - similar to an inkjet printer - and cellular imaging to automatically sort and deposit single cells into standard 96- and 384-well microplates.
The CloneSelect™
Single-Cell Printer™ Series
Combined with the CloneSelect™ Imager, researchers can now capture the journey of a single cell from the moment it is dispensed to the formation of a colony several days later, thus providing additional evidence of monoclonality.
CloneSelect Single-Cell
Printer Series
CloneSelect Imager
Monoclonality Verification
