Sample preparation
Efficient phenol-free miRNA extraction, ensuring high yield and quality
High versatility in handling different biological samples, including tissues, cells and liquid biopsy
Simple "bind-wash-elute" method for quick and easy miRNA isolation
Integrated contaminant removal of proteins, DNA and other potential
Automated sample preparation
Standardization of the miRNA isolation process for precise and consistent extraction of miRNA from small and variable samples.
Flexibility with options – full automated kit or convert well-established spin-column kits for automation
Convenient miRNA extraction for multiple samples, reducing hands-on time
Real-time monitoring and control of the miRNA extraction process
Quantification: qPCR and dPCR
Highly specific and sensitive detection of miRNA through locked nucleic acid (LNA) enhanced PCR assays from low-input and challenging sample types including biofluids and FFPE
Fast and simple qPCR workflow, in just 2–3 hours utilizing a universal cDNA synthesis step and miRNA-specific assays
Absolute miRNA quantification through digital PCR for increased precision and accuracy
More information about dPCR
LNA technology for single-nucleotide discrimination and reliable detection of any miRNA through qPCR and digital PCR
Profiling: NGS
Comprehensive miRNA profiling with minimal PCR and sequencing bias using unique molecular identifiers (UMIs) during library preparation
More information on miRNA sequencing
Convenient bead-based workflow, eliminating the need for gel purification, excision and elution
Reduced hY4 Y RNA in serum and plasma samples to enhance miRNA detection sensitivity
Accessible bioinformatics tools for easy-to-use gene expression analysis
Functional analysis and localization
miRNA inhibitors, miRNA mimics and target site blockers for functional studies of miRNA pathways and downstream targets
More information on miRNA functional analysis
Highly potent antisense oligonucleotide tools for both in vitro and in vivo applications without the need for formulation
High specificity and sensitivity of LNA oligonucleotides used in functional analysis and localization studies
Precise miRNA localization and spatial miRNA analysis of individual miRNAs within cells and tissues using LNA detection probes
Data analysis and interpretation
Simple graphical interfaces for the navigation and analysis of miRNA data – no coding required
Robust bioinformatics tools as an all-in-one toolkit for miRNA analysis
High accuracy through quality control measures and advanced algorithms to minimize errors
Comprehensive analysis for differential expression analysis, pathway analysis and target prediction