Roll over boxes to see which uses are closer to reality for patients, and which need more time in development. Toggle to see how some have moved along the maturity curve since 2014.
Ready or not:
Clinical uses of Digital Health apps appear all along the maturity spectrum.
• Diabetes
• Depression
• Anxiety
• Exercise
• Pain Management
• Dermatological Conditions
• Schizophrenia / Bipolar
• Multiple Sclerosis
• Autism
• Genitourinary Conditions
• Diabetes Prevention
• Arthritis
• Kidney Disease
• Pulmonary Rehab
• Cardiac Rehab
• Stress Management
• Alcohol Moderation
• Post-traumatic Stress Disorder (PTSD)
• Alcohol & Substance Abuse
• Sleep / Insomnia
• Cancer
• Smoking Cessation
• Parkinson’s Disease
• Hypertension
• Hearing Loss & Tinnitus
• Congestive heart failure (CHF)
• Stroke
• Alzheimer’s Disease
• Medication Management
• Healthy Eating / Weight Management
• Asthma
• Infectious & Parasitic
• Chronic Obstructive Pulmonary Disease (COPD)
• Atrial Fibrillation Screening
• Medication Refills
• Myocardial Infraction (MI)
• Hematology
• Dental
• Attention Deficit Hyperactivity Disorder (ADHD)
• Hyperlipidemia
• Epilepsy
• Pneumonia
• Vision
• Oral Diseases
• General HC Info
• Social Media
• Gastrointestinal Conditions (GI)
• Self-Diagnosis & Symptom Checking
• Finding a Healthcare Provider (HCP)
• Managing Clinical and Financial Records
• Medication Discounts
• Pregnancy
• Well Newborn
RCT published by Whitehouse et al (2017) suggested that the Therapy Outcomes By You (TOBY) app had mixed results in improving Autism Treatment Evaluation Checklist.
Autism
Stroke: Meta-analysis published by Liu et al (2017) showed that mobile health interventions have generally mitigated key stroke risk factors including glycemic control (HbA1c) and smoking cessation (abstinence).
Genitourinary Conditions: RCT published by Hoffman et al (2017) demonstrated the value of the Tät® app in improving urinary incontinence symptoms in women.
Pulmonary Rehab: RCT published by Bourne et al (2017) showed that "MyCOPD" app is non-inferior to face-to-face pulmonary rehab.
stroke, genitourinary conditions, pulmonary rehab
Four meta-analysis studies published by Hou et al (2016), Cui et al (2016), Bonoto et al (2017) and Wu et al (2017) showed that diabetes apps consistently delivered statistically and clinically significant HbA1c improvements in Type 2 Diabetics, with greater benefits in Type 2 Diabetics than Type 1 Diabetics, younger patients than older patients, and patients who received healthcare professional feedback via the app versus those who did not.
Diabetes
Cancer: RCT published by Denis et al (2017) showed that the "MoovCare" web app improved Overall Survival (OS) in lung cancer patients by 7 months vs. SoC control primarily via earlier and improved initiation of optimal treatment.
PTSD: RCT published by Kuhn et al (2017) showed that using "PTSD Coach" significantly improved PTSD symptoms relative to a waitlist condition control.
Arthritis: RCT published by Skrepnik et al (2017) demonstrated that knee osteoarthritis patients following Hylan G-F 20 treatment who used the "OA GO" app increased their mobility faster than a standard follow-up control group.
cancer, ptsd, arthriTis
Meta-analysis published by Mateo et al (2015) showed that RCTs in which mobile phone app intervention was used to promote weight-related health measures or physical activity showed weight loss benefits but no physical activity improvements.
Exercise
RCT published by Faurholt-Jepsen et al (2015) showed that an app for self-monitoring and clinical feedback from a physician did not deliver statistically significant benefits on depression or mania (Hamilton Depression Rating Scale and Young Mania Rating Scale, respectively) vs the control group.
Schizophrenia /
Bipolar
Observational study published by AlKlayb et al (2017) showed that the iTeethey™ app improved mothers' knowledge of oral hygiene.
Dental
Maturity in 2017
Changes
2014 to 2017
Maturity in 2017
Changes
2014 to 2017
Source: IQVIA AppScript Clinical Evidence Database, Aug 2017
Uses Eligible for Inclusion in Clinical Guidelines
Potential Disappointments
and More Study is Required
Use Eligible for Adoption into Clinical Practice
Uses Eligible for Evaluation in a Randomized Controlled Trial (RCT)
General Lack of Studies
Average Study Results
Multiple
Meta-analysis Studies
One
Meta-analysis
Multiple
RCT Studies
One
RCT Study
Multiple Observational Studies
One Observational Study
No Studies
Relative Quantity and Quality of Available Clinical Evidence
NOTABLE
ALL POSITIVE
ALL NEGATIVE
LIMITED
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Schizophrenia / Bipolar
Autism
Exercise
Diabetes
Cancer, PTSD, Arthritis
Dental
Stroke, Genitourinary Conditions, Pulmonary Rehab
