MenariniSearch-Overview Comprehensive Liquid Biopsy: Advancing Biomarker discoveries in clinical trials with cell-free RNA (cfRNA), cell-free DNA (cfDNA) and circulating tumor cells (CTCs)

Dive Deeper, Uncover More: Comprehensive RNA Sequencing for Unique Discoveries.

Enter a New Era of Testing That Redefines Possibilities.

Multiple Insights from Each Draw Point

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RNA SEQUENCING & CTC TESTING

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Why Work With Us

We Help You Enhance Your Clinical Trials Through

At Menarini Silicon Biosystems, we believe our unique approach to applying CellSearch and MenariniSearch technologies will embrace the transformative potential of your drug discovery or clinical trials efforts.

Creativity, Innovation, & Experimentation

Embrace the transformative potential from a single blood draw:

SINGLE BLOOD DRAW

Pharma/Lab Services

Circulating Tumor Cells

CTC Testing in drug development and clinical trials enables a deeper understanding of cancer biology, enhances patient stratification, assists in treatment decisions and contributes to the development of more effective and personalized cancer therapies

cfDNA, cfRNA, DNA, RNA

Comprehensive RNA sequencing is pivotal in unraveling the complexities of gene expression and molecular mechanisms, offering a deeper understanding of diseases, potential therapies and patient responses.

CTCs, cfDNA, cfRNA, DNA, RNA

Understanding the molecular characterization of circulating tumor cell will provide unprecedented information into cancer biology, treatment response and personalized medicine.

Latest news.

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Get in touch.

1 (877) 837-4339 us-info@siliconbiosystems.com

FILL & submit A contact form

people

International team. Professional people. Global Reach.

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Business Director

Adam Smith

Business Director

Adam Smith

Business Director

Adam Smith

Business Director

Adam Smith

Why us

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/03

2022

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/03

2018

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The Saint Expereince

The Lorum Collection

Comprehensive Molecular Characterization Heterogeneity in Tumors Tumor Biology and Functionality Resistance Mechanisms Biomarker Diversity and Patient Stratification Clinical and Research Implications Integrative Analysis

Holistic Analysis: Obtain a comprehensive cellular and molecular characterization, minimizing invasiveness, maximizing insights, and qualify study subjects accordingly Streamlined Processes: Simplify and accelerate your trials with streamlined testing, avoiding the complexities of multiple testing methods Real-Time Monitoring: Continuously monitor disease dynamic and treatment response, empowering informed decision-making at every stage

What if you could make timely adjustments to your research and clinical trials based on real-time insights from acurate genomic profiling?

LEARN MORE

Search the liquid. Search the tissue. Search more mutations.

Comprehensive Genomic Profiles

Analysis of the tumor microenvironment and immune infiltration Altered gene expression levels Gene mutations Gene fusions Gene amplifications and deletions Chromosome number alterations (CNAs) Tumor mutational burden (TMB) Regions with loss of heterozygosity (LOH) Approved targeted therapies and clinical trials Predictive biomarkers informing on targeted therapy and/or immunotherapy Signatures of prognostic relevance for specific tumor types

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Comprehensive Genomic Profiles

MenariniSearch

We use Illumina’s sequencing technology with our custom built proprietary library prep kits. Our extraction process has been finely crafted and mastered over many years. This enables us to provide you robust comprehensive RNA profiles. In addition to our wet lab, our bioinformatics supporting the comprehensive genomic profiles are powered by artificial intelligence which was co-developed among molecular pathologists, mathematicians, statisticians and scientists.

Technologies

We use Illumina’s sequencing technology with our custom built proprietary library prep kits. Our extraction process and has been finely crafted and mastered over many years. This enables us to provide you a robust comprehensive RNA profiles. In addition to our wet lab, our comprehensive genomic profiles are powered by artificial intelligence which was co-developed among molecular pathologists, mathematicians, statisticians and scientists.

Search the Liquid. Search the Tissue. Search More Mutations...

Comprehensive Genomic Profiles

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Liquid Biopsy

Hematological Malignancies

cfRNA Profiling cfDNA Profiling T&B-cell Clonality, EBV Gene Expression

Solid Tumors

cfRNA Profiling cfDNA Profiling HPV Gene Expression

284 cfDNA Genes >1,600 cfRNA Genes

Ask us how we are taking liquid biopsy to a whole new level!

Get in touch with our scientists:

cANCER TYPES

TECHNOLOGY

Pharma / ruo lab services

cAPABILITIES

Drug Development and Clinical Trials Real-Time Monitoring and Prognostic Value Understanding Tumor Heterogeneity

Comprehensive Molecular Profiling Uncovering Biomarkers and Targets Discovering Novel Insights Monitoring Treatment Responses

Real-Time Assessment of Treatment Efficacy Clinical Trial Stratification Facilitating Drug Development

Bone Marrow Biopsy

284 DNA Genes >1,600 RNA Genes

Hemotological Malignancies

RNA Profiling DNA Profiling T&B-cell Clonality, EBV Gene Expression

Tissue Biopsy

434 DNA Genes >1,600 RNA Genes

Solid Tumors

RNA Profiling DNA Profiling HLA Genotyping HPV, TMB, HRD, PD-L1 Gene Expression

Unravelling Rare Cells, Precisely Understand Molecular Signatures

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One Test Multiple Insights

We Help You Revolutionize Your Clinical Trials Through

Creativity, Innovation, & Experimention

Why Work With Us

Embrace the transformative potential from a single blood draw:

SINGLE BLOOD DRAW

Pharma/Lab Services

FILL & submit A contact form

1 (877) 837-4339 us-info@siliconbiosystems.com

Get in touch.

With our broad liquid biopsy solutions we enable you to identify more genetic alterations, empowering you to discover novel biomarkers and therapeutic targets that could enhance clinical trials and biomarker discoveries.

Multi Analyte

Various Sample Types

Quick Turn-Around Times

Global Presence

Circulating Tumor Cells Cell-free RNA Cell-free DNA DNA RNA

Peripheral Blood Plasma Cells Cerebrospinal Fluid (CSF) Fine Need Aspirates Tissue Biopsy

CellSearch: <3 Days Menarini Search: 10-14 days New Assay Development (User-defined): 13-18 weeks

The Only Lab That Offers Circulating Tumor Cells (CTCs) + Comprehensive RNA and DNA Profiles Across Most Cancer Types

>1000

8-13 Wks

<1%

NGS samples clinically validated for MenariniSearch Profiles

The time to develop biomarker specific “User-defined” assay

QNS Rate For tissue biopsy on MenariniSearch profiles

850+

Peer reviewed studies published featuring CELLSEARCH® Technology

Multiple Testing Methods

Single Test

CTCs

Menarini Silicon Biosystems

Other Labs