Identify changes within cell signaling or metabolic pathways that can be used to monitor disease or treatment response as potential prognostic biomarkers.
Biomarkerdiscovery
Study the role of cellular energy production, including glucose metabolism, to understand the mechanisms driving metabolic disorders.
Metabolicdisorders
Investigate cancer cell proliferation and the mechanisms driving tumorigenesis, invasion and metastasis. Examine how tumors undergo metabolic reprogramming and the pathways involved in tumor suppression.
Cancerbiology
Develop new therapeutic strategies that target key proteins. Reveal novel insights into pharmacodynamic effects of modulatory drugs.
Therapy targetsand resistance