Gene Expression and Death
Goncalves, P. et al. "Molecular signatures at imminent death: hemocyte gene expression profiling of shrimp succumbing to viral and fungal infections." Developmental and Comparative Immunology (2014)
Objective: measure gene expression levels of hemocyte immune response genes when exposed to white spot syndrome virus (WSSV) and Fusarium solani (fungal) in order to understand the molecular mechanisms driving shrimp-pathogen interactions to develop strategies to control disease outbreaks in shrimp production systems with L. vannameiUtilization of Standard BioTools™ products: • Biomark™ System• Nanoflex™ 4-IFC Controller• 96.96 Dynamic Array™ IFCs• Real-Time PCR Analysis Software Conclusions: • Genes that were monitored showed uregulation and down regulation over the time course study• Results reported can serve as immunomarkers for mortality events and could help reduce the loss in shrimp production systems
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SHRIMP CASE STUDY
Objective: The objective of this study was to measure gene expression levels of Hemocyte immune response genes when exposed to White Spot Syndrome Virus (WSSV) and Fusarium solani (fungal) in order to understand the molecular mechanisms driving shrimp-pathogen interactions to develop strategies to control disease outbreaks in shrimp production systems with L. vannamei. Utilization of Standard BioTools products: Biomark SystemNanoFlex 4-IFC Controller96.96 dynamic arraysReal-Time PCR Analysis Software Conclusions: Genes that were monitored showed up regulation and down regulation over the time course study. Results reported can serve as immunomarkers for mortality events and could help reduce the loss in shrimp production systems